Textbook in PDF format

This book provides the reader with insight into the advances that have taken place in the field of amide bond activation. It focuses on both the fundamental structural properties of the amide bond and the synthetic reactions mediated by transition-metals.
By discussing amide bond activation in terms of modern organic synthesis, the reader is provided with a thorough overview of the area and its crucial role in forging carbon-carbon and carbon-heteroatom bonds. Sample topics discussed within the work include:
Cross-coupling of amides
Amide bond activation by twisting and nitrogen pyramidalization
Electrophilic amide bond functionalization
Transition metal-catalyzed radical reactions of amides
Amide bond esterification, hydrolysis and transamidation
Classical bridged lactams and anomeric amides
Computational studies of amide C-N bond activation
Cross-coupling of esters by C-O activation
The book is immensely valuable to synthetic chemists in academia and the pharmaceutical industry who wish to gain an in-depth understanding of the concept of amide bond activation.
Bridged Lactams as Model Systems for Amidic Distortion
Modification of Amidic Resonance Through Heteroatom Substitution at Nitrogen: Anomeric Amides
Amide Bond Activation by Twisting and Nitrogen Pyramidalization
Transition-Metal-Free Reactions of Amides by Tetrahedral Intermediates
Electrophilic Amide Bond Functionalization
Transamidation of Carboxamides and Amide Derivatives: Mechanistic Insights, Concepts, and Reactions
Amide Bond Esterification and Hydrolysis
Activation of Amide C–N Bonds by Nickel Catalysis
Pd–NHC Catalysis in Cross-Coupling of Amides
Cross-Coupling of Amides Through Decarbonylation
Transition Metal-Catalyzed Radical Reactions of Amides
Weinreb Amide as a Multifaceted Directing Group in C–H Activation
Computational Studies of Amide C–N Bond Activation
Esters as Viable Acyl Cross-Coupling Electrophiles
Cross-Coupling of Aromatic Esters by Decarbonylation